一項(xiàng)最新研究業(yè)已證實(shí)基因芯片分析得出的高水平基因表達(dá)特征是可以重復(fù)的，能夠在臨床應(yīng)用中進(jìn)一步推廣。

基因芯片質(zhì)量控制(MAQC)研究是由美國(guó)食品藥品協(xié)會(huì)(FDA, Rockville, MD, USA)領(lǐng)導(dǎo)的合作研究。該研究包括來自私立和公立實(shí)驗(yàn)室的137位科學(xué)家。Affymetrix(Santa Clara, CA, USA)和其他基因芯片和試劑生產(chǎn)廠商參加了為期2年的初始設(shè)計(jì)，以驗(yàn)證基因芯片檢測(cè)數(shù)據(jù)的可重復(fù)性。該研究結(jié)果報(bào)道在2006年9月8日《自然生物技術(shù)》之上。
 
Study Determines MicroArray Data Reproducibility
 
A new study has demonstrated that at a high level, gene expression signatures generated by microarrays are repeatable, further advancing the field towards widespread use in clinical applications.

The MicroArray Quality Control (MAQC) study was a collaborative effort led by the U.S. Food and Drug Association (FDA, Rockville, MD, USA). The study included 137 scientists from private and public sector laboratories. Affymetrix (Santa Clara, CA, USA) and other microarray and reagent manufacturers participated in the two-year initiative designed to address the reproducibility of data generated from microarrays. The study’s results were reported in the September 8, 2006, issue of Nature Biotechnology.