根據(jù)近期對(duì)計(jì)算機(jī)斷層掃描檢查的研究結(jié)果，研究人員設(shè)計(jì)了一個(gè)模型來預(yù)測(cè)急性闌尾炎的嚴(yán)重程度。

Mayo診所的科學(xué)家檢查了105例年齡在15歲～69歲進(jìn)行腹部CT檢查后3天內(nèi)接受闌尾切除手術(shù)的患者資料。對(duì)CT掃描結(jié)果與急性闌尾炎實(shí)際嚴(yán)重程度進(jìn)行了比較。研究證實(shí)了CT結(jié)果與急性闌尾炎闌尾實(shí)際病變有相關(guān)性。這些結(jié)果被用來設(shè)計(jì)一個(gè)模型，當(dāng)與額外CT檢測(cè)聯(lián)合使用的時(shí)候，能夠幫助確定高度疑似急性闌尾炎的治療方案。

研究人員得出結(jié)論，研究達(dá)到了在不遠(yuǎn)的將來設(shè)計(jì)出預(yù)測(cè)模型的目標(biāo)，能夠根據(jù)疾病的組織學(xué)嚴(yán)重程度預(yù)測(cè)來對(duì)此類患者進(jìn)行分層。這些研究結(jié)果為隨后的前瞻性臨床試驗(yàn)提供了基礎(chǔ)，將使用預(yù)測(cè)性分層來確定手術(shù)干預(yù)時(shí)間的選擇。

這項(xiàng)研究發(fā)表在2004年11月的《外科檔案期刊》上。
 
CT Can Predict Severity of Appendicitis
 
Based on recent computed tomography (CT) findings, researchers have devised a model to predict the severity of acute appendicitis.

Scientists at the Mayo Clinic (Scottsdale, AZ, USA) examined 105 patients between the ages of 15 and 69 who underwent an appendectomy within three days after having an abdominal CT. Results of the CT scans were compared with the actual severity of acute appendicitis. The study demonstrated that CT gave results correlating with the actual condition of the appendix in acute appendicitis. These results were utilized to devise a model that could, when used in combination with additional CT measurements, help determine the best treatment course in patients strongly suspected of having acute appendicitis.

The researchers concluded that the study accomplished the goal of devising a predictive model that, in the near future, may help stratify such patients based on prediction of the histologic severity of the disease. It provides a foundation for a subsequent prospective trial that will use predictive stratification that will determine the need for and timing of operative intervention.

The study was published in the December 2004 issue of the journal The Archives of Surgery.