一種新型快速床邊診斷檢測能夠檢測尿液中的對乙酰氨基酚。這種方法叫做Triage TOX藥物篩查，已經獲得了美國食品藥品管理局的許可。

對乙酰氨基酚劑量過大是導致向美國中毒控制中心求助的首位原因，據估計在美國每年導致52000000中毒事件中的5％(275,000)。對乙酰氨基酚是世界范圍內使用最廣泛的止痛劑，是100種最常見非處方藥和處方藥之一。盡管這種藥物有著良好的安全譜，但是在故意服用大劑量或者服用超過150-200mg/kg體重劑量的時候會發(fā)生中毒。

根據美國國家臨床生物化學學會指導大綱，每一例疑似故意大劑量服用患者都應當在1小時以內進行對乙酰氨基酚篩查。Ken Buechler博士是Biosite公司(San Diego, CA, USA)總裁和首席科學官員，正是他開發(fā)了這項檢測方法。他指出：“因為Triage TOX藥物篩查使用Triage MeterPlus平臺，這就使得在床邊檢測在大約15分鐘之內就可以得到結果。我們相信這能夠減少檢測對乙酰氨基酚的時間。”

公司提供了3種不同的分析組合能夠涵蓋8種主要藥物。這項檢測在說英語的國家以及經過當地主管機關批準的國家廣泛應用。
 
Drug Screen for Acetaminophen

A novel, rapid point-of-care (POC) diagnostic test detects acetaminophen in urine. Called Triage TOX drug screen, the test has been cleared by the U.S. Food and Drug Administration (FDA).

Overdose from acetaminophen is the leading cause for calls to the U.S. Poison Control Centers and is estimated to represent 5% (275,000) of the 5.2 million U.S. total toxic exposures annually. Acetaminophen is one of the most widely used analgesics in the world and is found in more than 100 common over-the-counter and prescription products. While the drug has an excellent safety profile, toxicity can occur after intentional overdose or acute ingestion of 150-250 mg per kg of body weight.

According to the U.S. National Academy of Clinical Biochemistry guidelines, every patient suspected of intentional drug ingestion should be screened for acetaminophen in one hour or less,” noted Ken Buechler, Ph.D., president and chief scientific officer of Biosite Incorporated (San Diego, CA, USA), which developed the test.
“Because the Triage TOX drug screen uses the Triage MeterPlus platform, which produces results in approximately 15 minutes at the point of care, we believe it can improve turnaround time for acetaminophen.”

The company is offering three different combinations of analytes to cover the eight major classes of drugs. The tests will be available in English-speaking countries worldwide and in other countries upon approval by local regulatory agencies.